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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 22, Number 4
BKCSDE 22(4)
April 20, 2001 

 
Title
Unusual Cytotoxic Phenethylamides from Xenorhabdus nematophilus
Author
Seunguk Paik, Young Hwan Park, Seong Il Suh, Hyun Su Kim, In Sun Lee, Myung Kwang Park, Chun Soo Lee, Sun Ho Park
Keywords
Xenorhabdus nematophilus, Phenethylamides, Xenorhabdins.
Abstract
Three simple carboxamides incorporating the phenethylamine moiety have been isolated from strain XR-NC of a symbiotic bacterium Xenorhabdus nematophilus. Their structures were identified by spectroscopic data and synthesis. The compounds exhibited significant cytotoxicities against human cancer-cell line, viz. the gastric adenocarcinoma, colon adenocarcinoma and lung adenocarcinoma.
Page
372 - 374
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