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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 25, Number 12
BKCSDE 25(12)
December 20, 2004 

 
Title
Synthesis of Tetrahydrocarbazole Derivatives as Potent β3-Adrenoceptor Agonists
Author
Jae Du Ha, Seung Kyu Kang, Hyae-Gyeong Cheon, Joong-Kwon Choi*
Keywords
β3-Adrenoceptor, Tetrahydrocarbazole, Arylethanolamine, Antiobesty
Abstract
A series of 2-(3-chlorophenyl)-2-hydroxyethylamine derivatives containing a tetrahydrocarbazole linker were prepared and evaluated for their β3-adrenoceptor agonistic activity. Several compounds showed potency comparable to CL-316243.
Page
1784 - 1790
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