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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 28, Number 10
BKCSDE 28(10)
October 20, 2007 

 
Title
Nanoliter Reactor Arrays for Antibiotic Study
Author
Jin-Won Park
Keywords
Nanoliter, Reactor, Arrays, Vesicles, Gramicidin
Abstract
It is demonstrated in this study that the nanoliter reactor arrays with an inkjet printing, can be used for high throughput screen of antibiotic function. As a model antibiotic, gramicidin was used in this study. The gramicidin embedded lipid vesicles were immobilized on the surface in the nanoliter reactor structure with control of the volume in the nanoliter reactor. By dispensing acidic drops into the reactor, the gramicidin function was monitored. The technique developed in this research also has a great potential to be used for discovery of drugs.
Page
1709 - 1714
Full Text
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