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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 29, Number 10
BKCSDE 29(10)
October 20, 2008 

 
Title
Synthesis and Characterization of Novel Amino Acid-conjugated Poly(aspartic acid) Derivatives
Author
Seung Il Kim, Seok Kee Min, Ji Heung Kim*
Keywords
Nanoparticle, Poly(aspartic acid), Amphiphilic copolymer, L-Lysine
Abstract
Novel poly(aspartic acid) derivatives conjugated with L-lysine moieties and their amphiphilic analogs were synthesized and characterized. The chemical structures of these polymers were confirmed using FT-IR and 1HNMR spectroscopy. The physicochemical properties of amphiphilic copolymers were characterized using an electrophonetic light scattering spectrophotometer (ELS) and transmission electron microscopy (TEM). These results indicated a stable nanoparticle formation within aqueous media. These polymers have potential applications in the pharmaceutical and cosmetic fields as delivery vehicles for bioactive molecules.
Page
1887 - 1892
Full Text
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