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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 29, Number 11
BKCSDE 29(11)
November 20, 2008 

 
Title
Design and Synthesis of a Cyclopentene Scaffold Mimicking Oseltamivir as a Novel Neuraminidase Inhibitor
Author
Fushan Piao, Joon Hee Hong
Keywords
Neuraminidase inhibitor, Zanamivir, Oseltamivir, Cyclopentene scaffold
Abstract
The first synthesis of a cyclopentene version of oseltamivir as a novel neuraminidase inhibitor was achieved via the key cyclopentenone intermediate 4, which was prepared via syn-elimination from ketone derivative 2.
Page
2221 - 0
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