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Bulletin of the Korean Chemical Society (BKCS)

ISSN 0253-2964(Print)
ISSN 1229-5949(Online)
Volume 33, Number 3
BKCSDE 33(3)
March 20, 2012 

 
Title
Facilitated Protein-DNA Binding: Theory and Monte Carlo Simulation
Author
Kihyun Park,* Taejun Kim, Hyojoon Kim*
Keywords
Diffusion-influenced reaction, Facilitated diffusion, Protein-DNA binding, Dimension reduction, Exact solution
Abstract
The facilitated diffusion effect on protein-DNA binding is studied. A rigorous theoretical approach is presented to deal with the coupling between one-dimensional and three-dimensional diffusive motions. For a simplified model, the present approach can provide numerically exact results, which are confirmed by the lattice-based Monte Carlo simulations.
Page
971 - 974
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